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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9e52bd37f9e44332f6e27a867d7f543058081a1d9479c8c50c0f5750ec4720' 
  AND token = '4a7OxfV6MFA4sQstVKrgrukcYsqPhSbB/fefgz425kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}