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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80aa21f28b573d9cee6fbae5d508f11dd0d9b98fc3f4cc2ed946daaf59a263ef' 
  AND token = 'L3f/nOt3cZYU0In6JrJeQFg6UkX0hTVlgQuf40QqjNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}