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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff4f6716b3cc957a68eb89c75ab8aaaf13d49b4218c3562a1937f20bab89c56' 
  AND token = 'R4oiUkQU9BoXwcj7Rs+7qyjwbxSiDNYTebkznzs3AUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}