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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd622c7f8385af09c6608341e9d583223907b9e9569929761bfc018d64df241d5' 
  AND token = 'RzmdIFe/LkohhkBkppRiTEhlHDs9ix9Kn3cvTDX7XEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}