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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06dd08b69bdf6ea9d05ff9dc815d9014bb41ad6da812d49829e68bb715f21233' 
  AND token = 'WteMR9szjoKa2+mQ/D8RMJnwRfcwr/FI2kgapY6LUzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}