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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b78190e95b2ce551f157ecabbee796dc2d61d2efdec434c3bee6d6846a5348' 
  AND token = 'JTIXvjvGjpsD0DJzDj/bk5g6sn5PZohP30la9RMYrX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}