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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6531db1f4349f8f9dcb6f9cc24ec928324c2d551d06c9b3edaa72df4e6869200' 
  AND token = 'eOi1KuaSR1CJl6M0L7MmgxvsjSKMHnQoBfUtaSVNQQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}