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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fdc6e1498789cdfac3b499f73bebddec808ff73508719806b9579c119c4452c' 
  AND token = 'Aq1SXIHLnIzy/v9cu/OXWurONkVl7jUYf1vsSVOf+T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}