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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a8a88aa9ed9d93c5475431a0965891d0557a3ea82e2135aa9452407335f4cd2' 
  AND token = 'U4FAa3QNhY/2DI8lc0MewTIVvEmyoLdl0H1SELT6aG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}