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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6db8de47b2f8c8b106d373da9cf46c48f6362096af643bb4a258e799e6ed455' 
  AND token = '2bsS1cp3UaQ1JNSvkD+iNYHyruBGAKlpx+MB47Uu7/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}