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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643e95d3e05d9ecd1ff509eb95c54ba1f09bf82b76a6d4650a5979a871803e46' 
  AND token = '0nDGDBTEW37Y5YDc0X3ZGhnBNMFoR7KkThOn6tLQp6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}