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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15244ff1179b4e071bd436df480d3c186b5aa09d899a59191c29fbe4bdc4e8a8' 
  AND token = 'L6y4smxiUwhKQSXzuQT/exqh7MNZyy7Xj3eLZntUQAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}