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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f47e4e442410f170b8dd6f87b6b72c3996b7b1691b1991345aff5024091121' 
  AND token = 'HTxlwxU+lqG62zIQ+y7ovIKsxshQUcsrQRY7q2Ncx44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}