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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4500c9e6e908a8e199540785657690dd88e5c174ea59881a314271b546cd955' 
  AND token = 'VGRqJEO92653zcz5nMGcp+7fKdi8EoFne7o0lN88fQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}