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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b210222076aa1dee0643eec34d9944ecf93024ef8519cdeee6f32bd2f2dff53' 
  AND token = 'o90QI+V7+iED+CNxIoxsKIs1I+v3WdBR9m+VaOP9F+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}