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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15398592741e275ae220273c5e4395ccc8086f97c303fce193ad185fb6af8c2b' 
  AND token = 'fcRy1wzEI2CUHfL/+toMtb7OtePyfwqeTt56qu6TdEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}