SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e2c8d03a1f2b14f251f67d591e73979ea424b2c74e2252995069b7210bc013' 
  AND token = '57X7vV1CRczrusLuA3q6swd9bBjaEsF8Xzf6ZkTq3Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}