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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618f3adb49fad78de7a2f6e042814d147415da0a3f530c70a2702f50b25c3c4f' 
  AND token = 'Tb/WvqCJt82AUDL8dkPlg+NYVU4NKvWWnpkfNHPF/oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}