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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce72dd7fa1d95d8b067bf20f10247ac949823ff23ada2c1420d7c25478724102' 
  AND token = 'UJnQUS4gLSImuhJyybn8GHTNZwl1k5/qyRnIf2AlTRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}