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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6a1b9d442de20489b4e539c499cd9ab7788deb9f63f1be3c6217c4b4922079' 
  AND token = 'TygCmq72dzBFX5nZbPSIyL2yOv7zFPjghLiHPa9ydu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}