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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0efbbfdf63bea74f0b42d1929299c7b1ffae02249080c3b44a4b3964ef23a55' 
  AND token = 'l1X+mLpKsZzrdOiCHp0AaDeBHgN3RBdDD0JhxRGA3r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}