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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '802f1936ff690cb77358a0e246c913975c2d6c07b496ab8b73e911bb59ef2e08' 
  AND token = 'TuRAPU0mH+9a1W7BMA7vKNi2tLKoCwstEREpDMhUT8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}