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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810d21dc854249c0361605739abeccedf5f9885ac09c77a983150ac2167dd958' 
  AND token = 'XRlLM7S8FTN8QuHj31o//i0U45B65mmqDr4drjVPGIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}