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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51628333eaab7dcfe715b443316e5d181771f8e8e2defa84d9999b2fa97c2f1d' 
  AND token = 'T+MTwtZ7XLQAJTcVfdM/4hh80Z/oe4DSt74atMKJDK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}