SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f30864a3dd9a6513c14cf83e4eb2bb3f0f790e2c598f7da739c73688d133f66' 
  AND token = 'V8z16rIPUdYjhUxoy7a862wABYu3y+lzDv6nL3tOwD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}