SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18995bf9aeaead7c186c465581677663aa23216ad22296d2be9a0f6861e9c230' 
  AND token = 'j/UU7ZAINAzVC826793e4TNUpZjW0KIc3pIuvSCTLKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}