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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db656c56b2bf180200927d327bfa849ea5a0aeb3b54e8c75264ad458d93af47' 
  AND token = '/WMTbPBM6C0j29S97tYEPHvpIH7wHCK2EJGxvthI/mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}