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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441627d24fada047ec3112afb009bf32982d33dbc11d3a0921b00e65458a147f' 
  AND token = 'rqlqIi/WBDA8/sGyhVJKS2zRFA1k6ltTUki0aauke/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}