SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb5d95c3dceca47ac537e247b853099d087e51e0b8b5b138a77dc5f584d2cba' 
  AND token = 'm/qiwur/axxa12+mG9KPsozRsrT+Q1sg3Y6dryG2SDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}