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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b306c4599d54e32206c59076bc6b0210bea76a05a3c69c878e01b20e51136e' 
  AND token = '58gJd0aQkDVA+CPbK0WaFOJyayLMRCDy0gb/7yaiUzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}