SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346c0e2214d23db1e3a774a7cede243c002044d8aee72d6690e35cf4358a4690' 
  AND token = 'yaey6KK8/h+Jz8LAg/mheArt2NrvO0SUJMMYWcwCiME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}