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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5204cf4b55003407cb66eb8591ce049763d8dd4eab360edbaacacb20bfa15fe5' 
  AND token = 'F1+Ket9PNNz5OG0L3ZrZjd29zDsG2kuRkeP/1Vko/GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}