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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b246b779d0c9726c1bba249c540d111c6f3771042df4bbcf1977c1fc5c7efc6d' 
  AND token = 'qWSc1m2K4wi/rR6xqJ6XkDqllyXZMV/pZlqZbvqNxGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}