SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5803c3c6155475557d57af5aa873ea32f69611c96e5b5230dd9b309c7c0e9d33' 
  AND token = 'CYaQr4xhJdc6pQIigZoILCyPVx/3vlh/e6SCdYu7ElU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}