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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58cf7445efd1e6b49eb793905fc02f716c72c1c722801d0380b10f7e99467301' 
  AND token = 'Hnkjji6Q2DeP+JXmWxNFbJUQaGUM9+AR8SRKdp6Wm9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}