SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '114f986e0e3a626c6af8bc1d02b0c11a71096b2fad64351900e3e7260ff492bb' 
  AND token = 'DVnS0+h76oeLjRjffs5/kgKa9IJ6HrCqkX7I+3BjODw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}