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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5065b7ce1c33a14dc698fceb728b550fa5f63a0cbd09f5a497f9d64faba5db4a' 
  AND token = 'p+hFx3jLTqhIBUG98xOnVRdFEW48HO3OheQwR2d92bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}