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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc0335e04fa0034e424ba2797c81da6458f43f8ca982e11838cd342efbc7f196' 
  AND token = 'qT1xpmSLMkUGvtcfW8q+Ha1OZm+a1iPmavuFb93S8Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}