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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a7fd88da8fa60b3937c7521e52b7119c34875fe0c48cb73d4085ceb12eba59' 
  AND token = 'mbfsQwStTZn+PitxA8+5Gxg1FRSWfCCnfgzc05w0qUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}