SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcca953e3539e21e1a0c4a888c93585c2df3e0b34ca3dd4098ee274d74086b21' 
  AND token = 'zgK99bV1jQ+ILctsO+4SpoS9lrI6/qUBVYbz6RT+APo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}