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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f25b146c3841cea40237aff671f7188e372e59113499f5eb9e307bd58122e0' 
  AND token = '3wY7wrpY/0x1qnet+ijK/JrD3Wm3x7rPFWAgpdQ6ooc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}