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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5fd7d69a3888b2d186340b7f6727eb30db7e34f4d48988a43c60297a5f05fa5' 
  AND token = 'A0viakANWRK3R5glVVY+iJrmfeoIVO0yhszTkMA7bfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}