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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d720684c0362ea38fc4ba2957ec8db497f566473ce83585d17ea22409d0876' 
  AND token = 'GXITDoXIhJPpmc38DDMkP8WHM+6hVN22es3+urXgOjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}