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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e07140e4ac500caac653d88abbb660082fe7afa1b44e40ed94b32423390def' 
  AND token = 'FCpiNCDsbfDS5eJVnOGFlvPyNDgEt0ugf/fMrvjBRxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}