SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224129061309cd72a1e03cf7417e9fc1016e6bc8dbb3b34409d2bfe754b3bc0a' 
  AND token = 'Zqvu6tKQV321isJ/Xp5iVhXWNYBkT/Z6SH8CejEYOeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}