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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f35dd76277235ffa945cf12930de3cf4c3edc018050acef72f2499d40e8c7231' 
  AND token = 'fx4UjeYi0F+q8QDMTalKr3zkQSpU5Ow25/rKzpVKFfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}