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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13d66cc1611b2fb7aaaa0c12fb60cf45574242972dc1662a46b3f02cde03098' 
  AND token = 'xNSRklvUCDHcPUm7Edpc9mkIaDi5UyCe/OCIkW6thQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}