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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2581d4decfb1eaeadcbabb6d517d9a1a0d06156e57b65b714ec2fe0c89ff87' 
  AND token = 'GOHbs0M1bGRZVqg7bwVyY+/9jYeiuZHfult2e8kS9z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}