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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54240c17fb30a3ea4b8bbd78da36da4e8a3d75d40eb3ee27b9c889d5e7bcff6' 
  AND token = 'HkblKA+OoxDAKn6/nh25j52NO0V2HKrvBcXmFf0mTN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}