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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1983120719db5da2100f021250073d57a8e384f1122ffca2dec4edbe7eb62f1a' 
  AND token = 'KJhesnZ9dzoSEgL9VtgljZhioBfwmJDosQdPb6Eh1c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}